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degree in Biochemistry from Olabisi Onabanjo University, Ago-iwoye, and University of Ibadan, Ibadan, Nigeria respectively. Anal Biochem. 3 . All analyzed dataset to support the conclusions of this article is included as tables in the uploaded supplementary files. The antioxidants in Justicia carnea helps protect the liver and the heart from toxic agents and free radicals. Corroborating with the results of the antioxidant system and weight of the liver, continuous exposure to higher dose (1200mg/kg) of JCEE could result in hepatic damage. The effect of the ethanol extract of Justicea carnea (JC) leaves in phenylhydrazine induced-anemia albino rats on haematological and lipid profile parameters was investigated. Justicia carnea does not cause miscarriage or congenital birth defects. 2008;108(9):14807. Valko M, Leibfritz D, Moncol J, Cronin MTD, Mazur M, Telser J. Oral acute toxicity study on J. carnea ethanol extract (JCEE) was carried out according to Lorke [15] method using the total of twelve (12) albino rats in two phases. The reaction is terminated by the addition of 2ml of dichromoacetic acid mixture (potassium dichromate (5%) and glacial acetic acid; 1:3v/v) and heated at 60C for 10min. Faiza R, Waqas KK, Adeel M, Muhammad G. Detection of bioactive fractions of Justicia adhatoda leaves. Where, A=absorbance, TV=total volume, SV=sample volume, =extinction coefficient, TP=total protein. Ethanol extract of J. carnea leaf elevated red blood cell, hemoglobin, packed cell volume and platelet count with significant increase at higher doses of extracts compared to the control. In this study, the aqueous leaf extract of Justicia carnea was used. Mukinda JT, Syce JA. 2. Medapa S, Singh GRJ, Ravikumar V. The phytochemical and antioxidant screening of Justicia wynaadensis. Ogbe RJ, Adoga GI, Abu AH. Mean corpuscular hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC) showed significant (p<0.05) increased at 50mg/kg while doses greater than 100mg/kg showed no significant difference compared to the control. Anal Biochem. The result from the kidney histology could be due to the presence of active secondary metabolites and daily dosing of the extract. Kidney weight of rats treated with JCEE showed no significant difference with exception in 800mg/kg JCEE that demonstrated significant reduction. It is a creeping, perennial plant and grows up to 2 meters tall. Cookies, This site is protected by reCAPTCHA and the Google, Justicia scheidweileri (Purple Shrimp Plant), Justicia americana (American Water-Willow), Want Garden Inspiration? Some people would rather chew the leaves, while others add to meals or brew into a tea (in combination with other plants). Higher doses (>500mg/kg) of extract significantly (p<0.05) increased RBC, hemoglobin and platelet compared to the control. The weight of liver and kidney of rats were measured immediately after excising the organs and is presented in Table2. Further study assessing the kidney indices (urea, creatinine and electrolytes) is however encouraged to ascertain the safety of the plant extract on renal function. Effects of ethanol leaf extract of Justicia carnea on serum SOD
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side effect of justicia carnea